rs10692285 Archives

Sudden death indel polymorphism

Dec 19, 2016James KohlAdaptations, Alternative Splicings, Autophagy, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations1540T/C, 370A, adaptive variant, amino acid substitution, autophagy, base pair, bio-functional information, biophysically constrained, chromosome 2, ectodysplasin A receptor, EDAR gene, EDAR variant, energy-dependent, energy-dependent biodiversity, energy-dependent polymorphism, fixation, indel, insertion/deletion, John L. Leonard, knockin mouse, loss- and gain-of-function model, microRNA, mRNA, Peter Berean, physiology of reproduction, polymorphism, rs10692285, Rs3827760, single nucleotide polymorphism, sudden unexplained death, supercoiled DNA, Val370Ala

An insertion/deletion polymorphism within 3’UTR of RYR2 modulates sudden unexplained death risk in Chinese populations. …different alleles of rs10692285 could alter the local structure of RYR2 mRNA and microRNA (miRNA) binding. See for comparison: Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant The differences between the 370A knockin mouse phenotypes […]