RNA-mediated amino acid substitutions Archives - Autophagy

God vs host-derived creation of virus-driven pathology

Aug 23, 2017James KohlAdaptations, Alternative Splicings, Autophagy, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, Model Organisms, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variationsanti-entropic virucidal energy of sunlight, autophagy, base pairs, biophysically constrained biodiversity, chirality, COMPARATIVE PSYCHOLOGY, ecosystem, electrons to ecosystems, Enigmatic Spacer Repertoires, ethology, host-derived creation, host–viral dynamics, human idiocy, Human Pheromones, hydrogen-atom transfer in DNA base pairs in solution, infected plankton, Jay R. Feierman, Male Gait Perception, neuroendocrinology, nutrient energy-dependent RNA-mediated reprogramming, one-carbon metabolism, Origin of Reverse Transcriptase, pheromone-controlled reproduction, Physical Strength, physiology of reproduction, phytoplankton function, RNA-mediated amino acid substitutions, structure of photons, ultraviolet radiation, viral latency, virus-driven pathology, viruses, vitamins and nutrients, Woese

Summary: The virus-driven theft of quantized energy forces cells to compete for nutrient energy-dependent RNA-mediated reprogramming in the context of the structure of photons, one-carbon metabolism, autophagy, and the physiology of reproduction, which links energy-dependent changes in chirality from base pairs to RNA-mediated amino acid substitutions. Host-derived viral transporter protein for nitrogen uptake in infected […]

Energy-dependent physical and biophysical constraints (9)

Jul 28, 2017James KohlAdaptations, Autophagy, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, Model Organisms, Nutrigenomics, RNA Directed, RNA-directed DNA methylation, RNA-mediated gene silencing, Variations, What's in the News3D chromatin structure, autophagy, base pairs, chirality, de novo Creation, degradation of messenger RNA, DNA organization, enzymes, G-protein-coupled receptors, GnRH, gonadotropin-releasing hormone, hormones, interphase, microRNAs, mitosis, mitotic cells, model, negative supercoiling, organized genomes, physiology. pheromone-controlled reproduction, Receptors, RNA-mediated amino acid substitutions, Scent of Eros, single nucleotide polymorphisms, supercoiled DNA, Virus-driven energy theft

Summary: Energy determines genome compaction because activity in the nucleus is energy-dependent. Chromatin chains link energy-dependent changes in base pairs from single nucleotide polymorphisms to fixation of RNA-mediated amino acid substitutions in organized genomes via the physiology of pheromone-controlled reproduction. It’s all about the base. Energy-dependent physical and biophysical constraints (8) ChromEMT: Visualizing 3D chromatin […]

Theistic evolutionists fight back and lose

Feb 24, 2017James KohlAdaptations, Alternative Splicings, Autophagy, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations, What's in the News3D reconstructions, amino acid sequence, anti-entropic virucidal energy, antigenic changes, autophagy, Bill Gates, biodiversity, biophysically constrained, C. elegans, Caenorhabditis elegans, cell type differentiation, chirality, class II fusion proteins, coding sequences, critical thinking skills, Dauer Formation, de novo Creation, DNA repair, dysfunctional, ecological adaptations, endogenous RNA interference, Endogenous RNAi Pathways, energy-dependent codon optimality, evolutionary relationships, Femtosecond blasts of UV light, function, genes, Human Embryos, hydrogen atoms, innate immune system, Malnourished children, Mutational Processes, neurons, nfluenza virus, nutrient energy-dependent, nutrient energy-dependent structure, P. Pacificus, Paul Allen, pheromone-controlled reproduction, ridiculous claims, RNA-mediated amino acid substitutions, single amino acid, structure, sunlight, supercoiled DNA, theistic evolution, viral latency, Virus-driven energy theft

A giant neuron found wrapped around entire mouse brain Yuste and Eberwine would like to see 3D reconstructions of individual neurons compared to analyses of the genes expressed in those neurons. This may offer clues as to the type and function of each cell. The nutrient energy-dependent structure and function of all cell types in […]

Happy Darwin Day (2017)

Feb 12, 2017James KohlAdaptations, Alternative Splicings, Autophagy, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variationsanti-entropic virucidal energy, autophagy, biophysically constrained, biosynthetic pathways, cell type differentiation, Charles Darwin, chemistry, chirality, Codon optimality, conditions of life, coral reefs, Darwin Day 2017, de Vries, endogenous RNA interference, energy-dependent, energy-dependent creation, energy-dependent microRNAs, Eugene Koonin, Evolution-guided optimization, George Church, healthy longevity, Human Genome Engineering, Membrane Patterns, messenger RNA degradation, modern synthesis, molecular epigenetics, neo-Darwinian theorists, nutrient energy-dependent, Ontogenetic Information, physics, physiology of reproduction, RNA-guided, RNA-mediated, RNA-mediated amino acid substitutions, sunlight, supercoiled DNA, theistic evolution, viral hecatomb, viral latency, virus-damaged DNA, Zika virus

My series of blog posts about the refutation of theistic evolution by George Church led him to contact me via email. He asked why he would get credit for or against the refutations He claimed he was trained in quantum physics. He claimed that he has authored peer reviewed papers on protein folding, biodiversity, supercoiling, […]

Natural selection for codon optimality and quantum viruses

Feb 6, 2017James KohlAdaptations, Alternative Splicings, Autophagy, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variationsautophagy, biodiversity, biophysically constrained, cellular degradation, endogenous RNA interference, imino photons, Matti Pitkänen, messenger RNA degradation, microRNA precursor, microRNA/messenger RNA, microRNAs, protein folding chemistry, residues, RNA-mediated amino acid substitutions, temperature-responsive flowering, tipping point, Virus-driven energy theft

Life is Quantum Life is energy-dependent. Energy is information. Life is not quantum except in the context of hydrogen-atom energy transfer in DNA base pairs in solution. Claims that do not also address the effects of virus-driven energy theft fail to link what is know about quantum physics from the creation of the sun to […]

Virus-driven energy theft and premature death

Feb 1, 2017James KohlAdaptations, Alternative Splicings, Autophagy, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Nutrigenomics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variationsanti-entropic virucidal energy, autophagy, chirality, endogenous RNA interference, energy-dependent codon optimality, experimental evidence, innate immune system, lifespan-limiting active mechanisms, natural selection, RNA-mediated amino acid substitutions, sunlight, supercoiled DNA, Titorenko, virus-driven degradation of messenger RNA, Yeast mutants, yeasts to humans, Zika virus-damaged phenotypes

See also: Energy is information, RNA interference and healthy longevity Mitochondria operate as signaling platforms in yeast aging Aging is obviously energy-dependent. Theorists do not seem to know where the energy comes from or how genomic entropy is prevented. For the most recent example of what some researchers don’t know, see: Yeast mutants unlock the […]

Autophagy: from pre-mRNAs to microRNAs, enhancers, QTLs et al.

Jan 14, 2017James KohlAdaptations, Alternative Splicings, Autophagy, Diseases & Disorders, Ecology, RNA Directedamino acid optimality code, amino acids, anti-entropic energy, autophagy, biodiversity, chirality, Codon identity, Disease, energy-dependent changes in alternative splicings, Enhancer RNAs, eRNAs, Estrogen-dependent Transcriptional Activation, Health, maternal-to-zygotic transition, microRNA, molecular effectors, mRNA stability, ncRNAs, negative supercoiling, Non-coding RNAs, pH, pheromone-controlled, polyadenylation, pre-mRNA, pre-mRNAs, Regulation of autophagy, RNA-mediated amino acid substitutions, RNA-mediated cell type differentiation, supercoiled DNA, transcriptome expansion, Viral Infection of the Placenta, Zika virus

Nothing known to serious scientists links anything except energy-dependent changes in chirality to autophagy and biodiversity via RNA-mediated amino acid substitutions that differentiate all cell types in all living genera. That fact forces pseudoscientists to invent new terms to confuse the biologically uninformed masses who were taught to believe in the neo-Darwinian pseudoscientific nonsense of […]

Science journalists or paid propagandists? (3)

Jan 8, 2017James KohlAdaptations, Autophagy, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, VariationsAmino Acid Mixture, anti-entropic virucidal energy, ATP Production, ATP synthase, autophagy, chirality, electron transport chain, energy-dependent, epigenetic regulation, gene networks, increased exercise capacity, increasing organismal complexity, Molecular organization, nutrient energy-dependent, pheromone-controlled, RNA-mediated amino acid substitutions, signaling molecules

See: Science journalists or paid propagandists? (2) See also from the first blog post in this series: Science journalists or paid propagandists? Differential Expression of Putative Pheromone-detecting Cells and Receptors in the Olfactory Epithelium of an African Cichlid Fish The link from sunlight and chirality to nutrient energy-dependent reproduction is not addressed in the presentationss […]

Critical values expose virus-driven energy theft (2)

Jan 8, 2017James KohlAdaptations, Autophagy, Diseases & Disorders, Ecology, Model Organisms, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA–Mediated Epigenetic Heredity, VariationsASCP, autophagy, Autophagy fan club, biodiversity, biologically-based, biophysically constrained, Cephalopod Olfacton, chirality, Clinical Laboratory Scientist, Critical Values, de novo Creation, Embryonic Brain Development, fixation, G-protein-coupled receptors, gene-centric theory, H-bond network, human embryonic stem cells, interactome, lineage, multi-subunit proteins, neurogenesis, pH, phosphorylation, potential of hydrogen, protein folding chemistry, regulatory subunits, RNA SYNTHESIS, RNA-mediated amino acid substitutions, single cell RNA-seq, supercoiled DNA, synthesis of RNA, Virus-driven energy theft

Why Don’t The Amish Get Cancer? …the Amish commitment to simple, productive lives and clean, local food is benefiting their health in ways that the rest of America can only dream about. They exemplify what it means to be an ecologically adapted human population. See also: Past 5,000 years prolific for changes to human genome The […]

Critical values expose virus-driven energy theft

Jan 7, 2017James KohlAdaptations, Autophagy, biophotonics, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA–Mediated Epigenetic Heredity, VariationsASCP, autophagy, Autophagy fan club, biodiversity, biologically-based, biophysically constrained, Cephalopod Olfacton, chirality, Clinical Laboratory Scientist, Critical Values, de novo Creation, Embryonic Brain Development, fixation, G-protein-coupled receptors, gene-centric theory, H-bond network, human embryonic stem cells, interactome, lineage, multi-subunit proteins, neurogenesis, pH, phosphorylation, potential of hydrogen, protein folding chemistry, regulatory subunits, RNA SYNTHESIS, RNA-mediated amino acid substitutions, single cell RNA-seq, supercoiled DNA, synthesis of RNA, Virus-driven energy theft

Critical Values: is ASCP’s quarterly magazine with news and features covering trends of interest to pathologists and laboratory professionals alike. See for example: Attentive Clinical Laboratory Scientist Discovers First Human Case of Borrelia turicatae Critical Values spoke with technologist Dolli Lane, MLT(ASCP)CMCsCM, and the chief of the hematology section, Chris Boyd, MLT(ASCP)CM, about their findings. […]