Nov 1, 2016 James Kohl Adaptations , Alternative Splicings , Autophagy , biophotonics , Diseases & Disorders , Ecology , Human Brain , Human Pheromones , Light Energy , Model Organisms , Neuronal Plasticity , Nutrigenomics , Pharmacogenomics , Physics , RNA Directed , RNA methylation , RNA-directed DNA methylation , RNA-mediated epigenetic regulation of gene expression , RNA-mediated gene silencing , RNA-mediated toxicity , RNA–Mediated Epigenetic Heredity , Variations affects on behavior , alpha chains of hemoglobin , alternative splicing , amino acid replacements , amino acid substitutions , autophagy , biodiversity , biological regularities , chemotaxis , chimpanzee , chromatin , chromatin structure , complex patterns of diversity , coupled to a burst of cytokines , creation of pseudogenes , Cytokine Control , Data Integration , deletion , Developmental Gene Regulation , differential expression , DNA Base Pairs , ecological variation , energy-dependent changes , energy-dependent variations , enes , epigenesis , epigenetic effects , epigenetic imprinting , epigenetic landscape , epistasis , erythrocytes , fine-tuned energy-dependent functional structure , fixation of amino acid substitutions , functional constraints , G-protein-coupled receptors , gene regulatory systems , genomic duplication , genomic region , genomics , glycomics , gorilla , HBD evolution , healthy longevity , Hecatombic evolution , Hemoglobin Variants , horizontal gene transfer , hormone-activated , hormone-organized , human , Hydrogen-Atom Transfer , identical genes , indels , influenza virus , insertion , locus of genes , loss of miRNAs , metabolites , metabolomics , microRNA/messenger RNA balance , miRNA function , molecular defects , molecular mechanisms , multi-dimensional interactions , Multi-omic , mutation , National Microbiome Initiative , nucleotide substitution , nutrients , personalized medicine , pheromones , phototaxis , physical landscape , polycomb , polycombic ecological adaptation , pre-mRNA , Precision Medicine Initiative , predictive biomarkers , protein interactions , proteins , proteomics , pseudogene , purifying selection , quorum sensing , replication , RNA profiles , RNA viruses , RNA-mediated protein folding , RNA-protein interactions , segmental gene duplication , sex differences , silencing , Single nucleotide substitutions , Stable , supercoiled DNA , sustained depletion , thalassemia , Transcription , Transcriptomics , transposition , Virus-driven energy theft , viruses , β-Globin Cluster Evolutionary Constraints in the β-Globin Cluster: The Signature of Purifying Selection at the δ-Globin (HBD) Locus and Its Role in Developmental Gene Regulation Conclusion: … the results here presented indicate that purifying selection is driving not only HBD evolution but also its neighbor pseudogene, HBBP1. In the light of recent advances in the characterization of […]
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