Quantized energy-dependent microRNA-mediated autophagy (2)

Summary: A single genetic change provided complete protection against an invariably lethal dementia. A naturally occurring variant of the human prion protein completely prevents prion disease (2015) …mice expressing only PrP V127 were completely resistant to all prion strains, demonstrating a different molecular mechanism to M129V, which provides its relative protection against classical CJD and […]

Dobzhansky 1973 and precision medicine

MicroRNA-34 directly targets pair-rule genes and cytoskeleton component in the honey bee Our findings point to miR-34-5p as novel regulatory component in the complex molecular cascade that governs insect segmentation and to a broader role of miRNAs in the early development due to the detection of mature transcripts from both 5p and 3p arms for […]

Energy-dependent alternative splicings 1996 – 2016

Highlights: 1) Alternative splicings of messenger RNA link the sun’s anti-entropic virucidal energy as information to DNA repair. 2) DNA repair links fixation of amino acid substitutions in supercoiled DNA to healthy longevity. 3) Supercoiled DNA protects all organized genomes from virus-driven energy theft and genomic entropy. 4) Genomic entropy is less likely to occur […]

The futility of The Battlefield FB group

Apparently, Paul Hartley blocked me from further discussion of his OP about dinosaurs and gladiators before I could ask if he thought “The Battlefield” is a “false flag” group. Does anyone else think that?   If so, do you think it can survive publication of experimental evidence that links responsive supramolecular systems to stepwise changes […]

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