The tipping point (revisited): 68,000 publications

MicroRNA  Items: 1 to 20 of 68011 (earlier today, on 12/21/17) See for example: In Vitro Validation of miRNA-Mediated Gene Expression Linked to Drug Metabolism 12/20/17 The approaches described can be employed broadly for the validation of miRNA-mediated negative regulation of any gene. Determining miRNA-mediated regulation of enzymes and transporters affecting drug metabolism is a critical […]

MicroRNAs GnRH and the failure of sex research

Summary: “The Bull Sperm MicroRNAome and the Effect of Fescue Toxicosis on Sperm MicroRNA Expression” accurately represents what is known about food energy-dependent RNA-mediated cell type differentiation in species from soil microbes to humans. MicroRNAs are not new players in the hypothalamic control of fertility and the effects of food odors and pheromones on microRNAs […]

Mutations: the "driving force" behind human brain complexity?

Evolutionary Psychology Crap in New Scientist There is a reason why domestic violence is so widespread, says David Buss, an evolutionary biologist at the University of Texas in Austin: it carries a selective advantage, tied with reproductive success. Larry Moran wrote: There’s something seriously wrong with evolutionary psychology. And there’s something seriously wrong with respectable […]

Energy-dependent purifying selection / autophagy (4)

Energy-dependent purifying selection / autophagy (3) My question: What is an abiotic environment? See: “abiotic factors found in aquatic systems may be things like water depth, pH, sunlight, turbidity (amount of water cloudiness), salinity (salt concentration), available nutrients (nitrogen, phosphorous, etc.), and dissolved oxygen (amount of oxygen dissolved in the water). Abiotic variables found in […]

Epigenetics and autophagy vs mutations and evolution (7)

RNA interference (RNAi) fails to protect all cell types from virus-driven energy theft. The effect on some cell types cannot be controlled. That’s because nutrient energy-dependent endogenosymbiosis and the pheromones-controlled physiology of reproduction protect the organized genomes of species from microbes to humans. Billions of waster dollars have been spent with no end to the […]

Epigenetics and autophagy vs mutations and evolution (3)

On the Origin of Species voted most influential academic book in history Excerpt: Darwin used meticulous observation of the world around us, combined with protracted and profound reflection, to create a book which has changed the way we think about everything – not only the natural world, but religion, history and society,” he said. “Every […]

Epigenetics and autophagy vs mutations and evolution (2)

Plants send light to roots to ‘see’ underground My comment: Sending light requires an energy-dependent link from hydrogen-atom transfer in DNA base pairs in solution to supercoiled DNA, which protects all organanized genomes from virus-driven energy theft and genomic entropy. See Schrodinger (1944) Excerpt: Indeed, in the case of higher animals we know the kind […]

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