humans Archives - Autophagy

Epigenetics and autophagy vs mutations and evolution (2)

Nov 11, 2016James KohlAdaptations, Alternative Splicings, Autophagy, Diseases & Disorders, Ecology, Neuronal Plasticity, Physics, RNA Directed, RNA-directed DNA methylation, Variationsalternative splicing, autophagy, chemoautotrophic, chemoheterotrophic, Chemosynthesis, chromatin structure, Drosophila, epigenetic imprinting, epigenetics, evolution, humans, mice, mutations, polycomb, pre-mRNA, silencing, symbiogenesis, telomeric regions, Transcription, yeast

Plants send light to roots to ‘see’ underground My comment: Sending light requires an energy-dependent link from hydrogen-atom transfer in DNA base pairs in solution to supercoiled DNA, which protects all organanized genomes from virus-driven energy theft and genomic entropy. See Schrodinger (1944) Excerpt: Indeed, in the case of higher animals we know the kind […]

RNA-mediated repurposing in microbes and adaptations in primate brains

Mar 9, 2015James KohlAlternative Splicings, Autophagy, Ecology, Human Pheromones, Model Organisms, RNA-directed DNA methylationAmino Acid, autophagy, brain stem cells, chimpanzees, DNA methylation, Dobzhansky, Evolutionary resurrection, gorilla, Human-specific gene, humans, natural selection, neocortex, nutrient-dependent, olfactory receptor gene, pheromone-controlled, repurposing, RNA-directed, RNA-mediated, substitution, Svante Paabo

Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion Excerpt: “…the C-terminal 47 amino-acids of ARHGAP11B (after lysine-220) constitute not only a unique sequence, resulting from a frameshifting deletion (fig. S10), but also are functionally distinct from their counterpart in ARHGAP11A.” My comment: Co-author Svante Paabo is the senior author of this 2003 publication: […]