eukaryote Archives

Quantized energy-dependent mTORC1 and autophagy

Conclusion: One side of this representation of the global metabolic shift links food energy-dependent microRNA biosynthesis to healthy longevity. The other side of the global metabolic shift links the virus-driven theft of quantized energy from autophagy to catabolism. Biologically uninformed theorists link catabolism from mutations to evolution. Serious scientists link fixation of RNA-mediated amino acid […]

More refutations of neo-Darwinian nonsense

Dec 23, 2016James KohlAdaptations, Alternative Splicings, Autophagy, Diseases & Disorders, Ecology, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variationsangstroms to ecosystems, Archaea, archaeal hecatomb, autophagy, bacteria, biophysically constrained, Carl Woese, Codon optimality, common ancestor, conserved molecular mechanisms, coral dinoflagellate symbionts, CRISPR Bioterror Threat, directed evolution, domains of life, energy-dependent changes, energy-dependent RNA-mediated DNA methylation, eukaryote, experience-dependent adaptations, hydrogen-atom transfer in DNA base pairs in solution, learning and memory, microRNA flanking sequences, microRNA/messenger RNA, Motif-mediated interactions, mutagenesis, nutrient-dependent pheromone-controlled, pathology, phage display-derived peptides, physiology of reproduction, RNA-mediated amino acid substitutions, supercoiled DNA, Virus-driven energy theft, Virus-mediated, Weasel Word Way

New CRISPR–Cas systems from uncultivated microbes In bacteria, we discovered two previously unknown systems, CRISPR-CasX and CRISPR-CasY, which are among the most compact systems yet identified. Notably, all required functional components were identified by metagenomics, enabling validation of robust in vivo RNA-guided DNA interference activity in E. coli. Interrogation of environmental microbial communities combined with […]