environment Archives - Autophagy

Energy-dependent structure and function: Until death (3)

Oct 11, 2017James KohlAutophagy, RNA Directedachiral glycine, agonist-induced changes, allosteric inhibition, antiviral response, ATP dependent, autophagy, BDNF Val66Met substitution, biophysically constrained vertebrate biodiversity, Bruce McEwen, Bull Sperm MicroRNAome, Circulating microRNA, dizocilpine, ecological variation, energy landscape, environment, epigenesis, epistasis, Evolutionary distance measurements, extracellular domain, feedback loops, Fescue Toxicosis, food odors, gating motions, genes, Genes/Domains identification, glycolysis, GnRH, GnRH receptor, gonadotropin-releasing hormone, human-specific COMT Val158Met substitution, Implementing sequence statistics, kinetic changes, NMDA receptor gating, Nobel Peace Prize, oxidative carbohydrate catabolism, OXIDATIVE PHOSPHORYLATION, pheromones, Phylogenetic tree building methods, Phylogenetic tree evaluation, physiology of reproduction, pre-stressed translational signature, Replication defective viral genomes, resonance energy transfer, RNA SYNTHESIS, RNA-mediated, Selection confirmation, Sequence alignments, sex, Sperm MicroRNA Expression, structurally distinct changes, structure-energy landscape, suicide, Suicide Prevention, transcriptome’s response, transmembrane states, virus-driven degradation of messenger RNA, Viruses in Human Semen, zinc

Energy-dependent structure and function: Until death (2) The COMT Val158Met polymorphism supposedly is not found in species other than humans See: Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles This is also the first study establishing the COMT*L allele as the derived allele unique to humans. Other organisms do not commit suicide. That […]

Energy-dependent structure and function: Until death (2)

Oct 11, 2017James KohlAutophagy, RNA Directedachiral glycine, agonist-induced changes, allosteric inhibition, antiviral response, ATP dependent, autophagy, BDNF Val66Met substitution, biophysically constrained vertebrate biodiversity, Bruce McEwen, Bull Sperm MicroRNAome, Circulating microRNA, dizocilpine, ecological variation, energy landscape, environment, epigenesis, epistasis, Evolutionary distance measurements, extracellular domain, feedback loops, Fescue Toxicosis, food odors, gating motions, genes, Genes/Domains identification, glycolysis, GnRH, GnRH receptor, gonadotropin-releasing hormone, human-specific COMT Val158Met substitution, Implementing sequence statistics, kinetic changes, NMDA receptor gating, Nobel Peace Prize, oxidative carbohydrate catabolism, OXIDATIVE PHOSPHORYLATION, pheromones, Phylogenetic tree building methods, Phylogenetic tree evaluation, physiology of reproduction, pre-stressed translational signature, Replication defective viral genomes, resonance energy transfer, RNA SYNTHESIS, RNA-mediated, Selection confirmation, Sequence alignments, sex, Sperm MicroRNA Expression, structurally distinct changes, structure-energy landscape, suicide, Suicide Prevention, transcriptome’s response, transmembrane states, virus-driven degradation of messenger RNA, Viruses in Human Semen, zinc

Energy-dependent structure and function: Until death (1) Terry Crews details alleged sexual assault by ‘high level’ Hollywood exec “This whole thing with Harvey Weinstein is giving me PTSD. Why? Because this kind of thing happened to ME…” Crews tweeted Tuesday. This claim helps to link the celebrity status of Hollywood victims like Robin Williams to […]

Energy-dependent structure and function: Until death (1)

Oct 11, 2017James KohlAutophagy, Diseases & Disorders, Human Brain, Human Pheromones, Model Organisms, Neuronal Plasticity, RNA Directed, RNA-mediated epigenetic regulation of gene expression, Variationsachiral glycine, agonist-induced changes, allosteric inhibition, antiviral response, ATP dependent, autophagy, BDNF Val66Met substitution, biophysically constrained vertebrate biodiversity, Bruce McEwen, Bull Sperm MicroRNAome, Circulating microRNA, dizocilpine, ecological variation, energy landscape, environment, epigenesis, epistasis, Evolutionary distance measurements, extracellular domain, feedback loops, Fescue Toxicosis, food odors, gating motions, genes, Genes/Domains identification, glycolysis, GnRH, GnRH receptor, gonadotropin-releasing hormone, human-specific COMT Val158Met substitution, Implementing sequence statistics, kinetic changes, NMDA receptor gating, Nobel Peace Prize, oxidative carbohydrate catabolism, OXIDATIVE PHOSPHORYLATION, pheromones, Phylogenetic tree building methods, Phylogenetic tree evaluation, physiology of reproduction, pre-stressed translational signature, Replication defective viral genomes, resonance energy transfer, RNA SYNTHESIS, RNA-mediated, Selection confirmation, Sequence alignments, sex, Sperm MicroRNA Expression, structurally distinct changes, structure-energy landscape, suicide, Suicide Prevention, transcriptome’s response, transmembrane states, virus-driven degradation of messenger RNA, Viruses in Human Semen, zinc

The structure-energy landscape of NMDA receptor gating …using single-molecule Forster resonance energy transfer (smFRET), we map the energy landscape of the first transmembrane segment of the Rattus norvegicus NMDA receptor under resting and various liganded conditions. These results show kinetically and structurally distinct changes associated with apo, agonist-bound, and inhibited receptors linked by a linear […]

Autophagy is the antiphage defense strategy

Dec 8, 2016James KohlAutophagy, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredityanti-entropic, Antiphage Defense Strategy, autophagy, bacterial growth, biodiversity, bobtail squid, communication, conditions of life, developmental changes, energy-dependent symbiosis, environment, gene expression, genetic networks, healthy longevity, immune system, longevity, McFall-Ngai, metabolic networks, model organisms, molecular mechanism, natural selection, nutrient-dependent, pathology, pheromone-controlled, quantum biology, quantum consciousness, quantum physics, quorum sensing, reproduction, sunlight, Thermotolerance, Vibrio anguillarum, Vibrio fischeri, virucidal energy, Virus-driven energy theft

The “Antiphage Defense Strategy” in Vibrio anguillarum is called autophagy by many serious scientists. It links nutrient energy-dependent pheromone-controlled quorum sensing to viral latency, healthy longevity, symbiosis, reproduction, and biodiversity from microbial species to humans. For an evolutionary approach to energy-dependent autophagy that fails to address any aspect of how virus-driven energy theft causes all […]