budding yeast Archives

Base pairs, amino acids and phenotypes

Nov 20, 2016James KohlAdaptations, Alternative Splicings, Autophagy, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variationsassumptions, autophagy, biophysically constrained, budding yeast, circadian rhythms, combinatorial post-transcriptional gene-expression networks, Disease, DNA variation, energy-dependent, fruitfly, GWAS, immune response, inferences, innate immune system, mammalian cells, mathematical models, missing links, operons, oxidative metabolism, physiology of reproduction, polycomb, polycombic ecological adaptations, post-transcriptional events, RNA regulons, SNPs, stress response, supercoiled DNA

Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase DNA repair by homologous recombination (HR) underpins cell survival and fuels genome instability, cancer, and evolution. Autophagy is the established link from energy-dependent changes in base pairs and RNA-mediated amino acid substitutions to DNA repair in the context of polycombic […]