biological regularities Archives

Polycombic ecological adaptation as a science, not a theory (2)

Nov 1, 2016James KohlAdaptations, Alternative Splicings, Autophagy, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variationsaffects on behavior, alpha chains of hemoglobin, alternative splicing, amino acid replacements, amino acid substitutions, autophagy, biodiversity, biological regularities, chemotaxis, chimpanzee, chromatin, chromatin structure, complex patterns of diversity, coupled to a burst of cytokines, creation of pseudogenes, Cytokine Control, Data Integration, deletion, Developmental Gene Regulation, differential expression, DNA Base Pairs, ecological variation, energy-dependent changes, energy-dependent variations, enes, epigenesis, epigenetic effects, epigenetic imprinting, epigenetic landscape, epistasis, erythrocytes, fine-tuned energy-dependent functional structure, fixation of amino acid substitutions, functional constraints, G-protein-coupled receptors, gene regulatory systems, genomic duplication, genomic region, genomics, glycomics, gorilla, HBD evolution, healthy longevity, Hecatombic evolution, Hemoglobin Variants, horizontal gene transfer, hormone-activated, hormone-organized, human, Hydrogen-Atom Transfer, identical genes, indels, influenza virus, insertion, locus of genes, loss of miRNAs, metabolites, metabolomics, microRNA/messenger RNA balance, miRNA function, molecular defects, molecular mechanisms, multi-dimensional interactions, Multi-omic, mutation, National Microbiome Initiative, nucleotide substitution, nutrients, personalized medicine, pheromones, phototaxis, physical landscape, polycomb, polycombic ecological adaptation, pre-mRNA, Precision Medicine Initiative, predictive biomarkers, protein interactions, proteins, proteomics, pseudogene, purifying selection, quorum sensing, replication, RNA profiles, RNA viruses, RNA-mediated protein folding, RNA-protein interactions, segmental gene duplication, sex differences, silencing, Single nucleotide substitutions, Stable, supercoiled DNA, sustained depletion, thalassemia, Transcription, Transcriptomics, transposition, Virus-driven energy theft, viruses, β-Globin Cluster

Evolutionary Constraints in the β-Globin Cluster: The Signature of Purifying Selection at the δ-Globin (HBD) Locus and Its Role in Developmental Gene Regulation Conclusion: … the results here presented indicate that purifying selection is driving not only HBD evolution but also its neighbor pseudogene, HBBP1. In the light of recent advances in the characterization of […]