Energy-dependent autophagy prevents the degradation of messenger RNA

Quantized energy-dependent mTORC1 and autophagy

Conclusion: One side of this representation of the global metabolic shift links food energy-dependent microRNA biosynthesis to healthy longevity. The other side of the global metabolic shift links the virus-driven theft of quantized energy from autophagy to catabolism. Biologically uninformed theorists link catabolism from mutations to evolution. Serious scientists link fixation of RNA-mediated amino acid […]

Energy as information and constrained endogenous RNA interference (3)

See also: Energy as information and constrained endogenous RNA interference (2) The Scope (Febrary 4, 2017) On World Cancer Day, we’re featuring some of the most exciting research developments of the past year. First up? Yoshinori Ohsumi, Nobel laureate, whose research could save your life. 2016 Nobel Prize Winner Yoshinori Ohsumi’s Discoveries Could Change How […]

More refutations of neo-Darwinian nonsense

New CRISPR–Cas systems from uncultivated microbes In bacteria, we discovered two previously unknown systems, CRISPR-CasX and CRISPR-CasY, which are among the most compact systems yet identified. Notably, all required functional components were identified by metagenomics, enabling validation of robust in vivo RNA-guided DNA interference activity in E. coli. Interrogation of environmental microbial communities combined with […]

The natural success of RNAi and failed treatment

see my other blog posts on m6A Dynamics of Human and Viral RNA Methylation during Zika Virus Infection Excerpt: …ZIKV infection alters m6A location in mRNAs, methylation motifs, and target genes modified by methyltransferases. Our results identify a mechanism by which ZIKV interacts with and alters host cell functions. Reported as: Zika virus infection alters […]

Pheromone-controlled autophagy

Reporting new theories of evolution that fail to address facts about how energy-dependent changes link angstroms to ecosystems via chromosomal rearrangements in all living genera is like reporting old theories that have been invalidated by experimental evidence of biologically-based cause and effect. See for example:  2016-04-20 Roberto Cazzolla Gatti. A conceptual model of new hypothesis […]

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