See first: The tipping point (revisited): 100K (1) 3/30/20 Excerpts: MicroRNA Involvement in Signaling Pathways During Viral Infection 3/10/20 MicroRNAs organize intrinsic variation into stem cell states 3/5/20 …naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology. Moving forward: Why do dozens of diseases wax and wane with the […]
Synopsis: If you do not understand the experimentally established facts… use caution if you attempt to compare the President of the USA to Hitler. If you tell me I am being disrespectful or condescending, you may be more embarrassed than Nobel Laureate, Jack Szostak, and be subjected to more ridicule than Neil deGrasse Tyson, who […]
The food energy-dependent “doubling up” on ‘junk DNA’ is biophysically constrained by the physiology of pheromone-controlled reproduction. The metabolism of food to species-specific pheromones links the conserved molecular mechanisms of RNA-mediated cell type differentiation in all individuals of all living genera to healthy longevity via what is known about amino acid substitutions in supercoiled DNA, which […]
Energy as information and constrained endogenous RNA interference poster presentation February 15, 2017 KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer February 23, 2017 These studies demonstrate that serial genetic changes at the Kras/KRAS locus are frequent in cancer and modulate competitive fitness and MEK dependency. Reported as: Genetic ‘balance’ may […]
Every great scientific truth goes through three stages. First, people say it conflicts with the Bible. Next they say it has been discovered before. Lastly they say they always believed it. –Louis Agassiz The series about refutations of theistic evolution continues. Creationists and two publications in “Nature” support the claims of young earth creationists who […]
Darwinism for the Genomic Age: Connecting Mutation to Diversification …the chief cause of our natural unwillingness to admit that one species has given birth to other and distinct species, is that we are always slow in admitting any great change of which we do not see the intermediate steps. (Darwin, 1859) Darwin put energy-dependent “conditions […]
Physicists: Desperate Acts Light-induced endogenous RNA interference in bioluminescent microbes links Schrodinger’s claims in “What is LIfe?” (1944) from a light-to-chemical pathway of information exchange in all living genera via amino acid substitutions in supercoiled DNA. All subsequent works on the evolutionary synthesis failed to link the anti-entropic virucidal energy of sunlight to Darwin’s “conditions […]
MicroRNA-34 directly targets pair-rule genes and cytoskeleton component in the honey bee Our findings point to miR-34-5p as novel regulatory component in the complex molecular cascade that governs insect segmentation and to a broader role of miRNAs in the early development due to the detection of mature transcripts from both 5p and 3p arms for […]
See for comparison: How Plant-Soil Feedback Affects Ecological Diversity Researchers examine how underground microbes and nutrients affect plant populations. The link from the physiology of nutrient-dependent pheromone-controlled reproduction in species from microbes to humans was placed into the context of Common crop chemical leaves bees susceptible to deadly viruses The honeybee model organism links the […]
Apparently, Paul Hartley blocked me from further discussion of his OP about dinosaurs and gladiators before I could ask if he thought “The Battlefield” is a “false flag” group. Does anyone else think that? If so, do you think it can survive publication of experimental evidence that links responsive supramolecular systems to stepwise changes […]
