achiral glycine Archives - Autophagy

Light-activated error free DNA repair (2)

Nov 22, 2017James KohlAdaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, VariationsA-to-I RNA editing, A2AR, achiral glycine, adenosine repletion, atoms to ecosystems, autophagy, chiral source of hydrogen atoms, curcumin, de novo changes in electrons, docosahexaenoic acid, ecological adaptations, Endogenous adenosine, energy-dependent, error-free RNA-mediated DNA repair, GnRH decapeptide, Mechanisms of Recombination, Neuroimmunology, neurological disorders, Niacinamide, Nicotinamide, nucleotides, osteoarthritis, pheromone-controlled reproduction, photoreductant source, physiology, production of nucleotides, quantized energy, recombination, ribonucleotide reductase, RNA editing, RNA-mediated, sunlight, supercoiled DNA, virus-driven degradation of messenger RNA

Summary: In the diagram and diatribes that accompany claims about de novo changes in electrons and the production of nucleotides, the amount of pseudoscientific nonsense becomes perfectly clear. Pseudoscientists start with energy-dependent changes but call the changes de novo changes in electrons. That allows the pseudoscientists to dismiss any facts about how the creation of […]

Energy-dependent structure and function: Until death (3)

Oct 11, 2017James KohlAutophagy, RNA Directedachiral glycine, agonist-induced changes, allosteric inhibition, antiviral response, ATP dependent, autophagy, BDNF Val66Met substitution, biophysically constrained vertebrate biodiversity, Bruce McEwen, Bull Sperm MicroRNAome, Circulating microRNA, dizocilpine, ecological variation, energy landscape, environment, epigenesis, epistasis, Evolutionary distance measurements, extracellular domain, feedback loops, Fescue Toxicosis, food odors, gating motions, genes, Genes/Domains identification, glycolysis, GnRH, GnRH receptor, gonadotropin-releasing hormone, human-specific COMT Val158Met substitution, Implementing sequence statistics, kinetic changes, NMDA receptor gating, Nobel Peace Prize, oxidative carbohydrate catabolism, OXIDATIVE PHOSPHORYLATION, pheromones, Phylogenetic tree building methods, Phylogenetic tree evaluation, physiology of reproduction, pre-stressed translational signature, Replication defective viral genomes, resonance energy transfer, RNA SYNTHESIS, RNA-mediated, Selection confirmation, Sequence alignments, sex, Sperm MicroRNA Expression, structurally distinct changes, structure-energy landscape, suicide, Suicide Prevention, transcriptome’s response, transmembrane states, virus-driven degradation of messenger RNA, Viruses in Human Semen, zinc

Energy-dependent structure and function: Until death (2) The COMT Val158Met polymorphism supposedly is not found in species other than humans See: Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles This is also the first study establishing the COMT*L allele as the derived allele unique to humans. Other organisms do not commit suicide. That […]

Energy-dependent structure and function: Until death (2)

Oct 11, 2017James KohlAutophagy, RNA Directedachiral glycine, agonist-induced changes, allosteric inhibition, antiviral response, ATP dependent, autophagy, BDNF Val66Met substitution, biophysically constrained vertebrate biodiversity, Bruce McEwen, Bull Sperm MicroRNAome, Circulating microRNA, dizocilpine, ecological variation, energy landscape, environment, epigenesis, epistasis, Evolutionary distance measurements, extracellular domain, feedback loops, Fescue Toxicosis, food odors, gating motions, genes, Genes/Domains identification, glycolysis, GnRH, GnRH receptor, gonadotropin-releasing hormone, human-specific COMT Val158Met substitution, Implementing sequence statistics, kinetic changes, NMDA receptor gating, Nobel Peace Prize, oxidative carbohydrate catabolism, OXIDATIVE PHOSPHORYLATION, pheromones, Phylogenetic tree building methods, Phylogenetic tree evaluation, physiology of reproduction, pre-stressed translational signature, Replication defective viral genomes, resonance energy transfer, RNA SYNTHESIS, RNA-mediated, Selection confirmation, Sequence alignments, sex, Sperm MicroRNA Expression, structurally distinct changes, structure-energy landscape, suicide, Suicide Prevention, transcriptome’s response, transmembrane states, virus-driven degradation of messenger RNA, Viruses in Human Semen, zinc

Energy-dependent structure and function: Until death (1) Terry Crews details alleged sexual assault by ‘high level’ Hollywood exec “This whole thing with Harvey Weinstein is giving me PTSD. Why? Because this kind of thing happened to ME…” Crews tweeted Tuesday. This claim helps to link the celebrity status of Hollywood victims like Robin Williams to […]

Energy-dependent structure and function: Until death (1)

Oct 11, 2017James KohlAutophagy, Diseases & Disorders, Human Brain, Human Pheromones, Model Organisms, Neuronal Plasticity, RNA Directed, RNA-mediated epigenetic regulation of gene expression, Variationsachiral glycine, agonist-induced changes, allosteric inhibition, antiviral response, ATP dependent, autophagy, BDNF Val66Met substitution, biophysically constrained vertebrate biodiversity, Bruce McEwen, Bull Sperm MicroRNAome, Circulating microRNA, dizocilpine, ecological variation, energy landscape, environment, epigenesis, epistasis, Evolutionary distance measurements, extracellular domain, feedback loops, Fescue Toxicosis, food odors, gating motions, genes, Genes/Domains identification, glycolysis, GnRH, GnRH receptor, gonadotropin-releasing hormone, human-specific COMT Val158Met substitution, Implementing sequence statistics, kinetic changes, NMDA receptor gating, Nobel Peace Prize, oxidative carbohydrate catabolism, OXIDATIVE PHOSPHORYLATION, pheromones, Phylogenetic tree building methods, Phylogenetic tree evaluation, physiology of reproduction, pre-stressed translational signature, Replication defective viral genomes, resonance energy transfer, RNA SYNTHESIS, RNA-mediated, Selection confirmation, Sequence alignments, sex, Sperm MicroRNA Expression, structurally distinct changes, structure-energy landscape, suicide, Suicide Prevention, transcriptome’s response, transmembrane states, virus-driven degradation of messenger RNA, Viruses in Human Semen, zinc

The structure-energy landscape of NMDA receptor gating …using single-molecule Forster resonance energy transfer (smFRET), we map the energy landscape of the first transmembrane segment of the Rattus norvegicus NMDA receptor under resting and various liganded conditions. These results show kinetically and structurally distinct changes associated with apo, agonist-bound, and inhibited receptors linked by a linear […]

Energy-dependent sensory maps (1996-2016)

Dec 30, 2016James KohlAdaptations, Alternative Splicings, Autophagy, Ecology, Human Brain, Human Pheromones, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations, What's in the Newsachiral glycine, adaptation toward distant phenotypic optima, aggressive brain cancer, alternative splicing, anti-entropic virucidal energy, autophagy, biologically-based cause and effect, biophysically constrained, brain cancer, Caribbean pupfishes, chemotaxis, chimeric antigen receptors, Codon optimality, cytochrome C, de novo Creation, De Novo Mutations, Developmental broadening, energy-dependent, energy-dependent autophagy, excitatory, excitatory maps, experience-dependent maturation, extreme trophic specialization, feedback loops, G-protein-coupled receptors, GnRH decapeptide, greater phenotypic difference, healthy longevity, inhibitory, inhibitory sensory maps, innate immune system, Jimmy Carter, light of evolution, light-induced energy-dependent changes in enzymes, melanoma, minimal mutation distance, minimal number of nucleotides, natural information processing, natural selection, NBD peptide, neuronal networks, pair-wise comparison of homologous amino acids, pathology, phototaxis, physiology of reproduction, pre-mRNA, RNA-mediated amino acid substitutions, sexual differentiation, supercoiled DNA, T cell effector, triplets of nucleotides, trophic specialization, tumor microenvironment, viral latency, virus-caused mutations

Developmental broadening of inhibitory sensory maps My summary: They help to detail how olfactory input causes the energy-dependent de novo creation of sensory maps, which are representations of the external world. The experience-dependent representations link chemotaxis and phototaxis to biophysically constrained behavior. The representations are systematically organized in brain structures throughout development. Simply put, the […]