The energy-dependent creation of odorant receptors links single nucleotide polymorphisms and microRNAs to fixation of RNA-mediated amino acid substitutions that differentiate all cell types in all individuals or all living genera in the context of the physiology of pheromone-controlled reproduction.

We established that fact in our 1996 Hormones and Behavior review of RNA-mediated cell type differentiation at a time when microRNAs were called pre-mRNAs. See our molecular epigenetics section: http://www.hawaii.edu/PCSS/biblio/articles/1961to1999/1996-from-fertilization.html

Since then, these are some of the Nobel Laureates who have extended what is known about RNA-mediated cause and effect to what is known about all food energy-dependent pheromone-controlled biodiversity.

2004 Richard Axel (US) and Linda Buck (US) for their discoveries of “odorant receptors and the organization of the olfactory system.

2016: Yoshinori Ohsumi of Japan for his work on autophagy—a process whereby cells “eat themselves”—which when disrupted can cause Parkinson’s and diabetes.

2017: US geneticists Jeffrey Hall, Michael Rosbash and Michael Young for their discoveries on the internal biological clock that governs the wake-sleep cycles of most living things.

Nothing that happens in the life of any organism happens outside the context of the food energy-dependent biophysically constrained creation of ATP and RNA. All serious scientists know that, and their works have placed the facts about cell type differentiation into the context of feedback loops and messenger RNA cycling since 1990. See: Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels https://www.nature.com/articles/343536a0

Each time you see a report that indicates something new about energy-dependent feedback loops has been discovered, ask what the authors are trying to do. Keep this in mind, so that you know the answer:

“Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge.” — Kalevi Kull http://www.huffingtonpost.com/suzan-mazur/kalevi-kull-censorship–r_b_10797646.html

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1 week ago

http://www.rna-networks.at/wp-content/uploads/2016/11/titel640d.png

This is the end of neo-Darwinian pseudoscientific nonsense. All variants are energy-dependent ecological adaptations. They link ... See more

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2 weeks ago
Update 22: Subatomic is LIVE on Kickstarter & Tom Vasel's GLOWING review of Cytosis · Cytosis: A Cell Biology Board Game

Subatomic is LIVE on Kickstarter https://www.kickstarter.com/projects/geniusgames/cytosis-a-cell-biology-board-game/posts/2074343

The link from quantum mechanics to quantum chemistry was reported ... See more

Hello Cytosis backers, Subatomic is now LIVE on Kickstarter! Subatomic: An Atom Building Game just went live this morning. We surpassed our funding goal in only a few hours and already hit our first ... See more

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2 weeks ago
The end of toxic chemo? Blocking vitamin B-2 may stop cancer

Excerpt: Mitochondria are energy-producing organelles found inside each cell.

My comment: The creation of anti-entropic virucidal light links the creation of ATP in the mitochondria to all ... See more

New drug candidate may change chemotherapy as we know it; this compound stops cancer cells from spreading and has no toxic side effects, a new study shows.

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1 month ago
Hashem Al-Ghaili

This is another plea for funding of a gene-centric approach to the synthesis of a protein. The plea ignores the facts about RNA-mediated amino acid substitutions that differentiate all cell types in ... See more

Opossums can neutralize almost all poisons!

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1 month ago
Nanoparticle gel controls twisted light with magnetism

The trick, the researchers found, was to twist the nanoparticles themselves by coating them with amino acids. The twist could be either right- or left-handed—a property called chirality.

Ask a ... See more

"Help me, Obi Wan Kenobi. You're my only hope." For many of those around at the release of Star Wars in 1977, that scene was a first introduction to holograms—a real technology that had been around ... See more

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1 month ago
Journals and Conferences on Genetics & Molecular Biology

ATP-independent negative supercoiling has since been linked via computational models to claims about 3 domains of life. In mathematical models, the ATP-dependent creation of RNA has not been linked ... See more

Computational Biology
============================================
Computational Biology is a branch of #biology that focuses on computational theoretical approaches to understanding complex ... See more

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1 month ago

https://scirate.com/arxiv/1709.07439 Figure 1. Biocatalytic cascade for optical detection of three amino acids, using two detection pathways: A) measurement of NADH at 340 nm, and B) conversion of ... See more

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1 month ago
A Concise Review of MicroRNA Exploring the Insights of MicroRNA Regulations in Bacterial, Viral and Metabolic Diseases. - PubMed - NCBI

Merck says: CRISPR IP we have some foundational patents, which have been granted outside US, in Europe, Australia and Canada already. if somebody wants to use it for therapeutic applications, we are ... See more

Mol Biotechnol. 2017 Dec;59(11-12):518-529. doi: 10.1007/s12033-017-0034-7. Review

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1 month ago
Ian Bremmer

Evolutionary determinants of genome-wide nucleotide composition https://www.nature.com/articles/s41559-017-0425-y

Clearly, the pseudoscientists will continue in 2018 to fly the plane into the face ... See more

Ready for 2017

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