RNA interference Archives

Autophagy-related microRNA-mediated disease treatment (1)

Aug 17, 2020James KohlAdaptations, Autophagy, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Physics, RNA interference, Variationsautoimmune diseases, autophagy regulation, Autophagy-Related Delivery, Dengue subgenomic RNA, diversity, ethnicity, how dengue virus adapts, inflammation, molecular mechanisms, Nanomaterials, naturally occurring autophagy, neoplastic transformation, Novel Cancer Treatments, oxidative stress, TRIM family regulatory region, vaccine-induced DNA damage, viral fragments, virus evolution, viruses

Nanomaterials for Autophagy-Related miRNA-34a Delivery in Cancer Treatment Indexed on PubMed 8/16/20 This article is part of the Research Topic Novel Cancer Treatments based on Autophagy Modulation View all 11 Articles 1) “…understanding of the molecular mechanisms controlling autophagy…is still far from being elucidated.” That is a lie. Good questions lead towards understanding. Question: How […]

The microRNA-mediated future of humanity (6)

May 2, 2020James KohlAdaptations, Alternative Splicings, biophotonics, Cytosis, Diseases & Disorders, Ecology, Model Organisms, Physics, RNA interferencealternative splicing, angstroms to ecosystems, carbon fixation, coherently organized biology, feedback loops, molecular epigenetics, nutritional epigenetics, Optogenetic activation, quantum coherence, remdesivir, RNA-dependent RNA polymerase, vaccines, Visual Time Perception

Olfactory specificity regulates lipid metabolism through neuroendocrine signaling in Caenorhabditis elegans3/19/20 Optogenetic activation or inhibition of the responsible olfactory neural circuit promotes the loss or gain of fat storage, respectively. To investigate the endocrine factors that mediate the communication between the olfactory neural circuit and the fat storage tissue, we focused on neuropeptides that are […]

The microRNA-mediated future of humanity (3)

Apr 24, 2020James Kohl1 CommentAdaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, Nutrigenomics, Pharmacogenomics, Physics, RNA interference, RNA-mediated gene silencingautophagy inhibition, cancers, coronavirus, CRISPR, enhanced autophagy, enyzme-dependent endogenous substrates, food energy-dependent pheromone-controlled autophagy, intermolecular interaction, microRNA biogenesis, phages, proof of concept, sunlight, upstream regulators of gene expression

Light-activated microRNA biogenesis has been linked from the pheromone-controlled physiology of reproduction to healthy longevity via protection from the virus-driven degradation of messenger RNA in all living genera. On 4/21/20 that fact was misrepresented as: Coronavirus has mutated into at least 30 different strains, Chinese study finds. The report was based on this non-peer-reviewed paper […]

The tipping point (revisited): 100K (2)

Apr 1, 2020James Kohl2 CommentsAdaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Model Organisms, RNA interference, Subatomicamino acid substitutions, atheists, cell type differentiation, Codon optimality, endogenous RNA interference, OXIDATIVE PHOSPHORYLATION, pseudoscientists, RNA SYNTHESIS, theorists

See first: The tipping point (revisited): 100K (1) 3/30/20 Excerpts: MicroRNA Involvement in Signaling Pathways During Viral Infection 3/10/20 MicroRNAs organize intrinsic variation into stem cell states 3/5/20 …naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology. Moving forward: Why do dozens of diseases wax and wane with the […]

Preprints obfuscate facts (3)

Feb 26, 2019James KohlAutophagy, Cytosis, Diseases & Disorders, Ecology, Light Energy, Model Organisms, RNA interference

See: Preprints obfuscate facts (1) from RNA-mediated.com and Preprints obfuscate facts (2) from MicroRNA.pro Photoperiod-dependent expression of MicroRNA in Drosophila (11/6/18) is one of 2173 search results for “microRNA” at @biorxivpreprints. All results can be compared to >83,500 published works from this PubMed search for microRNA The PubMed search links the energy-dependent creation of achiral […]

Autophagy automagically prevents cancer (2)

Jan 29, 2019James KohlAdaptations, Autophagy, Cytosis, Diseases & Disorders, Ecology, RNA interferenceFood, Microbiome-based cures, microRNA biomarkers, pheromones, RNA interference, viral latency

Study suggests how high blood pressure might contribute to Alzheimer’s 1/28/19, and this report on another article from the same issue of Nature Communications on 11/19/18 was also reported on 1/28/19 as New knowledge about the interactions of messenger RNAs and micro-RNAs during brain development …imbalance between cell types… can lead to this disease… and… […]

Autophagy automagically prevents cancer (1)

Jan 27, 2019James Kohl1 CommentAdaptations, Autophagy, Ecology, Model Organisms, RNA interferenceCRISPR, Dynamical Emergence, George FR Ellis, Henry Morris IV, immanent selection, Institute for Creation Research, microbiome, Phytoremediation

microRNA + autophagy See items 1-1088 See also: MicroRNA.pro Autophagic cell death restricts chromosomal instability during replicative crisis 1/23/19 …autophagy is an integral component of the tumour suppressive crisis mechanism and that loss of autophagy function is required for the initiation of cancer. Reported as: In surprising reversal, scientists find a cellular process that stops […]

Estranged ‘White Coat Notes’ blogger exposes human idiocy (1)

Jun 18, 2018James KohlAdaptations, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the Newsadaptations, alternative splicings, autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, model organisms, Neuronal Plasticity, Nutrigenomics, physics, RNA editing, RNA interference, RNA methylation, RNA-directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Scientific Discoveries, Subatomic, Variations, What’s in the News

Excerpt: Please pardon the overwhelming ignorance of those who failed to link what organisms eat from the quantized energy-dependent creation of microRNAs to healthy longevity via the pheromone-controlled physiology of reproduction and the transgenerational epigenetic inheritance of all morphological and behavioral phenotypes in species from microbes to humans. The ignorance of biologically uninformed theorists has […]

Darwinian adaptation: a clear evolutionary trail?

Dec 22, 2017James KohlAdaptations, Autophagy, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, RNA editing, RNA interference, RNA-directed DNA methylation, Subatomicadaptability, anti-entropic virucidal energy, astrobiological question, autophagy, Bacterial self-organization, common sense, creation of sunlight, Darwinian adaptation, Dobzhansky, Eshel Ben-Jacob, feedback loops, Feynman, George F R Ellis, McEwen, microRNA-mediated creation, neo-Darwinian evolution, odor receptors, olfaction, physiology of reproduction, Psychology, Schrodinger, Socioaffective Neuroscience, supercoiled DNA, Top-down causation, viral latency, water

Summary: The light harvesting occurs in the ocean and on land. It links the creation of sunlight from food energy to the physiology of pheromone-controlled viral latency in all living genera, and all serious scientists know that. Origins of photosynthesis in plants dated to 1.25 billion years ago The world’s oldest algae fossils are […]

The tipping point (revisited): 68,000 publications

Dec 21, 2017James KohlAdaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the Newsagriculture, Alphagenomix, Antiphage Defense Strategy, atoms to ecosystems, autophagy, cell type differentiation, classical physics, climate, creation of enzymes, drug metabolism, ecological adaptations, education, energy, food energy-dependent, funding, medical research, microRNA-mediated, microRNA-mediated gene expression, microRNAs, mutations, nutrient-dependent, pheromone-controlled, PLOSBLOGS, public health, quantum physics, regulation, Retraction Watch, scientific evidence, Trump administration, virus-driven degradation of messenger RNA, war on science

MicroRNA Items: 1 to 20 of 68011 (earlier today, on 12/21/17) See for example: In Vitro Validation of miRNA-Mediated Gene Expression Linked to Drug Metabolism 12/20/17 The approaches described can be employed broadly for the validation of miRNA-mediated negative regulation of any gene. Determining miRNA-mediated regulation of enzymes and transporters affecting drug metabolism is a critical […]