The tipping point (revisited): 68,000 publications

MicroRNA  Items: 1 to 20 of 68011 (earlier today, on 12/21/17) See for example: In Vitro Validation of miRNA-Mediated Gene Expression Linked to Drug Metabolism 12/20/17 The approaches described can be employed broadly for the validation of miRNA-mediated negative regulation of any gene. Determining miRNA-mediated regulation of enzymes and transporters affecting drug metabolism is a critical […]

The Scientist reports Szostak’s “honest error”

Top 10 Retractions of 2017 …Szostak’s lab could not reproduce the findings, which the group attributes to honest error. Please put the “honest error” into the perspective of what was reported in: Retraction Watch In retrospect, we were totally blinded by our belief [in our findings]… The claim that scientists were blinded by their belief […]

For God and Country

Trump challenges the CDC to remember 9/11

Synopsis: If you do not understand the experimentally established facts… use caution if you attempt to compare the President of the USA to Hitler. If you tell me I am being disrespectful or condescending,  you may be more embarrassed than Nobel Laureate, Jack Szostak, and be subjected to more ridicule than Neil deGrasse Tyson, who […]

Autophagy.pro vs Nature Publications Group

Autophagy is the antiphage defense strategy (James V. Kohl: December 8, 2016) Autophagy.pro was launched on 11 December 2017 See for comparison from the Nature Publications Group.  First, they try to establish a more complicated new definition with several different pathways Autophagy Autophagy is a process by which cellular material is degraded by lysosomes or […]

Vulgar Antagonists vs Quantum Effects

Exosome Cargo Could Be Drug Target For Neuropathic Pain My discussion attempt was removed by Dfm Prime, who claims to be a patient advocate for those who are suffering from neurological insult. See: Works at Neurosensory Neuroregenerative Research Foundation Publication: Catechol-O-Methyl Transferase Inhibition Reduces Symptoms of Hallucinogen Persisting Perception Disorder See for comparison: Oppositional COMT […]

Long-term adaptation replaces evolution (2)

The food energy-dependent “doubling up” on ‘junk DNA’ is biophysically constrained by the physiology of pheromone-controlled reproduction. The metabolism of food to species-specific pheromones links the conserved molecular mechanisms of RNA-mediated cell type differentiation in all individuals of all living genera to healthy longevity via what is known about amino acid substitutions in supercoiled DNA, which […]

God vs host-derived creation of virus-driven pathology

Summary: The virus-driven theft of quantized energy forces cells to compete for nutrient energy-dependent RNA-mediated reprogramming in the context of the structure of photons, one-carbon metabolism, autophagy, and the physiology of reproduction, which links energy-dependent changes in chirality from base pairs to RNA-mediated amino acid substitutions. Host-derived viral transporter protein for nitrogen uptake in infected […]

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