The microRNA-mediated future of humanity (6)

Olfactory specificity regulates lipid metabolism through neuroendocrine signaling in Caenorhabditis elegans3/19/20 Optogenetic activation or inhibition of the responsible olfactory neural circuit promotes the loss or gain of fat storage, respectively. To investigate the endocrine factors that mediate the communication between the olfactory neural circuit and the fat storage tissue, we focused on neuropeptides that are […]

The microRNA-mediated future of humanity (3)

Light-activated microRNA biogenesis has been linked from the pheromone-controlled physiology of reproduction to healthy longevity via protection from the virus-driven degradation of messenger RNA in all living genera. On 4/21/20 that fact was misrepresented as: Coronavirus has mutated into at least 30 different strains, Chinese study finds. The report was based on this non-peer-reviewed paper […]

The tipping point (revisited): 100K (2)

See first: The tipping point (revisited): 100K (1) 3/30/20 Excerpts: MicroRNA Involvement in Signaling Pathways During Viral Infection 3/10/20 MicroRNAs organize intrinsic variation into stem cell states 3/5/20 …naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology. Moving forward: Why do dozens of diseases wax and wane with the […]

A model of ecological adaptation

Trump-hating advocates of vaccines + GMOs (3)

MicroRNA.pro: Trump-hating advocates of vaccines + GMOs (1) RNA-mediated.com: Trump-hating advocates of vaccines + GMOs (2) microRNA + autophagy See items 1-1204 Scientific creationists from the Institute for Creation Research (ICR) and biologically uninformed neo-Darwinian theorists from Oded Rechavi’s group in Israel  have helped Trump-hating advocates of vaccines + GMOs in the same way. They […]

The tipping point (revisited): 68,000 publications

MicroRNA  Items: 1 to 20 of 68011 (earlier today, on 12/21/17) See for example: In Vitro Validation of miRNA-Mediated Gene Expression Linked to Drug Metabolism 12/20/17 The approaches described can be employed broadly for the validation of miRNA-mediated negative regulation of any gene. Determining miRNA-mediated regulation of enzymes and transporters affecting drug metabolism is a critical […]

Agilent technology and energy-dependent autophagy

The first step towards understanding the link from the creation of energy to metabolism-related cellular function is called energy phenotyping. It requires the  technology to measure energy-dependent changes in RNA-mediated metabolic switches via the RNA interference (RNAi) screening strategy. Endogenous RNAi must then be linked  to the prevention of the virus-driven degradation of messenger RNA […]

For God and Country

Trump challenges the CDC to remember 9/11

Synopsis: If you do not understand the experimentally established facts… use caution if you attempt to compare the President of the USA to Hitler. If you tell me I am being disrespectful or condescending,  you may be more embarrassed than Nobel Laureate, Jack Szostak, and be subjected to more ridicule than Neil deGrasse Tyson, who […]

Elsevier fails to support the concept of autophagy

Summary: Who lets biologically uninformed theorists make presumptions about evolution after all serious scientists have linked light-harvesting from energy-dependent changes in electrons to ecosystems in all living genera via natural selection for food energy-dependent codon optimality. Who lets them pretend not to know that the pheromone-controlled physiology of reproduction links autophagy to the transgenerational epigenetic […]